Kynurenic Acid Electrochemical Immunosensor: Blood-Based Diagnosis of Alzheimer’s Disease
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چکیده
منابع مشابه
Electrochemical immunosensor for the diagnosis of celiac disease.
A novel electrochemical immunosensing strategy for the detection of antibodies to tissue transglutaminase (tTG) in human serum is presented. The proposed immunosensor consists of the immobilization by physical adsorption of tTG from guinea pig liver on graphite-epoxy composite (GEC) electrodes. After the reaction with the human serum (containing the specific antibodies in the case of celiac dis...
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Celiac Disease (CD) is an autoimmune disorder, represented by the ingestion of gliadin protein usually found in wheat, barley and rye. CD is closely associated with genes that code HLA-II antigens, mainly of DQ2 and DQ8 classes. Small intestinal biopsy is considered the gold standard for diagnosis of celiac disease. In addition, the most sensitive tests for the diagnosis of celiac disease inclu...
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The first electrochemical immunosensor (EI) for the detection of antibodies against deamidated gliadin peptides (DGP) is described here. A disposable nanohybrid screen-printed carbon electrode modified with DGP was employed as the transducer's sensing surface. Real serum samples were successfully assayed and the results were corroborated with an ELISA kit. The presented EI is a promising analyt...
متن کاملDiagnosis of schistosomiasis japonica with interfacial co-assembly-based multi-channel electrochemical immunosensor arrays
Schistosomiasis control remains to be an important and challenging task in the world. However, lack of quick, simple, sensitive and specific sero-diagnostic test is still a hurdle in the control practice. The commonly employed enzyme-linked immuno-sorbent assay (ELISA) relies on the native soluble egg antigen (SEA) that is limited in supply. Here we developed an electrochemical immunosensor arr...
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A novel graphene-based voltammetric immunosensor for sensitive detection of okadaic acid (OA) was developed. A simple and efficient electrografting method was utilized to functionalize graphene-modified screen-printed carbon electrodes (GSPE) by the electrochemical reduction of in situ generated 4-carboxyphenyl diazonium salt in acidic aqueous solution. Next, the okadaic acid antibody was coval...
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ژورنال
عنوان ژورنال: Biosensors
سال: 2021
ISSN: 2079-6374
DOI: 10.3390/bios11010020